ESR1 protein (Nomascus leucogenys) - STRING interaction network

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ESR1

Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)

Predicted Functional Partners:

NCOA3

0.999

ESR2

0.999

MED1

0.997

SP1

0.997

NCOA1

0.997

SRC

0.997

NCOR1

0.996

NCOA2

0.995

AKT1

0.991

PGR

0.988

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	ESR1	ENSNLEP00000028045	ENSNLEP00000018707	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.991
AKT1	ESR2	ENSNLEP00000028045	ENSNLEP00000017213	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Estrogen receptor 2.	0.967
AKT1	PGR	ENSNLEP00000028045	ENSNLEP00000008712	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.503
AKT1	SRC	ENSNLEP00000028045	ENSNLEP00000048569	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.921
ESR1	AKT1	ENSNLEP00000018707	ENSNLEP00000028045	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.991
ESR1	ESR2	ENSNLEP00000018707	ENSNLEP00000017213	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Estrogen receptor 2.	0.999
ESR1	MED1	ENSNLEP00000018707	ENSNLEP00000000991	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.997
ESR1	NCOA1	ENSNLEP00000018707	ENSNLEP00000047649	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor coactivator.	0.997
ESR1	NCOA2	ENSNLEP00000018707	ENSNLEP00000013823	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor coactivator.	0.995
ESR1	NCOA3	ENSNLEP00000018707	ENSNLEP00000008440	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor coactivator.	0.999
ESR1	NCOR1	ENSNLEP00000018707	ENSNLEP00000017988	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor corepressor 1.	0.996
ESR1	PGR	ENSNLEP00000018707	ENSNLEP00000008712	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Uncharacterized protein.	0.988
ESR1	SP1	ENSNLEP00000018707	ENSNLEP00000021481	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Sp1 transcription factor.	0.997
ESR1	SRC	ENSNLEP00000018707	ENSNLEP00000048569	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Tyrosine-protein kinase.	0.997
ESR2	AKT1	ENSNLEP00000017213	ENSNLEP00000028045	Estrogen receptor 2.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.967
ESR2	ESR1	ENSNLEP00000017213	ENSNLEP00000018707	Estrogen receptor 2.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.999
ESR2	MED1	ENSNLEP00000017213	ENSNLEP00000000991	Estrogen receptor 2.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.991
ESR2	NCOA1	ENSNLEP00000017213	ENSNLEP00000047649	Estrogen receptor 2.	Nuclear receptor coactivator.	0.995
ESR2	NCOA2	ENSNLEP00000017213	ENSNLEP00000013823	Estrogen receptor 2.	Nuclear receptor coactivator.	0.983
ESR2	NCOA3	ENSNLEP00000017213	ENSNLEP00000008440	Estrogen receptor 2.	Nuclear receptor coactivator.	0.997

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