STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XRCC6X-ray repair cross complementing 6. (535 aa)    
Predicted Functional Partners:
XRCC5
X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.
   
 0.998
PRKDC
Protein kinase, DNA-activated, catalytic subunit.
    
 0.985
LIG4
DNA ligase.
   
 0.984
NHEJ1
Non-homologous end joining factor 1.
    
 0.976
DCLRE1C
Uncharacterized protein.
   
 0.959
PARP1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
   
 
 0.951
WRN
WRN RecQ like helicase.
   
 
 0.948
APLF
Aprataxin and PNKP like factor.
    
 
 0.938
LIG3
DNA ligase.
   
 0.919
TP53BP1
Tumor protein p53 binding protein 1.
    
 0.894
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.