Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SHOC2SHOC2 leucine rich repeat scaffold protein. (582 aa)    
Predicted Functional Partners:
MRAS
Muscle RAS oncogene homolog.
    
 0.993
KRAS
KRAS proto-oncogene, GTPase.
   
 0.989
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
 0.989
HRAS
HRas proto-oncogene, GTPase.
   
 0.988
NRAS
NRAS proto-oncogene, GTPase.
   
 0.983
PPP1CA
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.969
RRAS
RAS related.
    
 0.954
RRAS2
RAS related 2.
    
 0.949
PPP1CC
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.911
PPP1CB
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.897
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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