Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPG7SPG7 matrix AAA peptidase subunit, paraplegin. (773 aa)    
Predicted Functional Partners:
AFG3L2
AFG3 like matrix AAA peptidase subunit 2.
  
 
0.936
MAIP1
Matrix AAA peptidase interacting protein 1.
    
 0.931
SMDT1
Single-pass membrane protein with aspartate rich tail 1.
     
 0.867
YME1L1
YME1 like 1 ATPase.
   
 0.851
PHB2
Prohibitin.
   
 0.797
ENSNLEP00000035385
Prohibitin.
   
 0.797
ENSNLEP00000042144
Prohibitin.
   
 0.797
CLPX
Caseinolytic mitochondrial matrix peptidase chaperone subunit.
  
  
 0.795
PMPCA
Peptidase, mitochondrial processing alpha subunit; Belongs to the peptidase M16 family.
  
 0.761
MRPL1
Uncharacterized protein.
   
 
 0.754
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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