STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (622 aa)    
Predicted Functional Partners:
MAP2K5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
  
0.995
SMYD3
SET and MYND domain containing 3.
   
 
 0.952
PAK2
Non-specific serine/threonine protein kinase.
    
0.932
PAK1
Non-specific serine/threonine protein kinase.
    
0.932
MAP3K4
Mitogen-activated protein kinase kinase kinase 4.
    
0.927
MAP2K6
Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.
  
0.921
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
     
0.905
CCM2
CCM2 scaffold protein.
    
 0.763
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.
    
 
 0.682
SRF
Serum response factor.
    
 0.676
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.