Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SMDT1Single-pass membrane protein with aspartate rich tail 1. (107 aa)    
Predicted Functional Partners:
MCU
Mitochondrial calcium uniporter.
    
 0.996
MICU1
Mitochondrial calcium uptake 1.
    
 0.996
MCUB
Mitochondrial calcium uniporter dominant negative beta subunit.
    
 0.993
MICU2
Mitochondrial calcium uptake 2.
    
 0.987
MICU3
Mitochondrial calcium uptake family member 3.
    
 0.978
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin.
     
 0.867
AFG3L2
AFG3 like matrix AAA peptidase subunit 2.
     
 0.847
EDF1
Endothelial differentiation related factor 1.
   
    0.834
DCTN3
Uncharacterized protein.
   
  
 0.759
MAIP1
Matrix AAA peptidase interacting protein 1.
     
 0.759
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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