STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRSS53Serine protease 53; Belongs to the peptidase S1 family. (564 aa)    
Predicted Functional Partners:
MBNL1
Muscleblind like splicing regulator 1.
    
 
 0.767
NOVA1
NOVA alternative splicing regulator 1.
      
 0.740
CCL15
C-C motif chemokine.
     
 0.679
TNFSF12
TNF superfamily member 12; Belongs to the tumor necrosis factor family.
      
 0.656
CCL14
C-C motif chemokine.
      
 0.591
LOC100599403
PIPK domain-containing protein.
      
 0.541
PIP5K1A
Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha.
      
 0.541
MST1R
Macrophage stimulating 1 receptor.
    
  0.517
MET
Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]
    
  0.517
KLK7
Peptidase S1 domain-containing protein.
  
 
  0.494
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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