Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISCA2Iron-sulfur cluster assembly 2. (154 aa)    
Predicted Functional Partners:
ISCU
Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
  
 
 0.917
GLRX5
Glutaredoxin 5.
   
 0.892
IBA57
Iron-sulfur cluster assembly factor IBA57.
  
 
 0.891
ENSNLEP00000045065
Fe-S_biosyn domain-containing protein.
  
0.889
ISCA1
Iron-sulfur cluster assembly 1.
  
0.873
ENSNLEP00000027909
Fe-S_biosyn domain-containing protein.
  
 0.835
NFS1
Aminotran_5 domain-containing protein.
  
 
 0.833
ENSNLEP00000040645
Fe-S_biosyn domain-containing protein.
  
 0.823
HSCB
HscB mitochondrial iron-sulfur cluster cochaperone.
   
 
 0.684
SCLY
Selenocysteine lyase.
  
 
 0.670
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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