Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (992 aa)    
Predicted Functional Partners:
ITGB2
Integrin beta.
   
 0.999
ICAM1
Intercellular adhesion molecule 1.
   
 0.990
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.982
C3
Complement C3.
   
 0.979
ITGAX
Integrin subunit alpha X; Belongs to the integrin alpha chain family.
  
 
0.978
ITGAL
Integrin subunit alpha L; Belongs to the integrin alpha chain family.
  
 
0.957
SPI1
Spi-1 proto-oncogene.
   
 0.956
THY1
Ig-like domain-containing protein.
   
 0.956
JAM3
Junctional adhesion molecule 3.
    
 0.944
FGA
Fibrinogen alpha chain.
    
 0.937
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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