Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
AGMOAlkylglycerol monooxygenase; Belongs to the sterol desaturase family. (445 aa)    
Predicted Functional Partners:
ALDH3A2
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
  
 0.724
FA2H
Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]
      
 0.695
DCTD
dCMP deaminase.
      
 0.662
G1RMN4_NOMLE
FZ domain-containing protein.
      
 0.561
SORBS3
Sorbin and SH3 domain containing 3.
      
 0.555
ARHGAP6
Rho GTPase activating protein 6.
    
 
 0.552
LOXL3
Lysyl oxidase like 3.
    
 
 0.546
PNMT
Phenylethanolamine N-methyltransferase.
      
 0.545
CRPPA
CDP-L-ribitol pyrophosphorylase A.
      
 0.521
MEOX2
Mesenchyme homeobox 2.
 
    
 0.505
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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