Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MCUMitochondrial calcium uniporter. (352 aa)    
Predicted Functional Partners:
MICU1
Mitochondrial calcium uptake 1.
    
 0.999
SMDT1
Single-pass membrane protein with aspartate rich tail 1.
    
 0.996
MICU2
Mitochondrial calcium uptake 2.
    
 0.989
MCUB
Mitochondrial calcium uniporter dominant negative beta subunit.
  
 
0.989
MICU3
Mitochondrial calcium uptake family member 3.
    
 0.972
PHB2
Prohibitin.
     
 0.861
NDUFA8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
      
 0.805
NDUFB7
Uncharacterized protein.
      
 0.803
NDUFB10
NADH:ubiquinone oxidoreductase subunit B10.
      
 0.794
HTRA2
HtrA serine peptidase 2.
      
 0.794
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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