Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)    
Predicted Functional Partners:
GRIA2
Glutamate ionotropic receptor AMPA type subunit 2.
  
0.999
GRIA4
Glutamate ionotropic receptor AMPA type subunit 4.
   
 0.999
GRIA3
Glutamate ionotropic receptor AMPA type subunit 3.
  
0.999
CAMK2A
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.995
CNIH2
Cornichon family AMPA receptor auxiliary protein 2.
   
 0.975
CAMK2D
Calcium/calmodulin dependent protein kinase II delta.
   
 0.975
CACNG8
Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
   
 0.974
CACNG2
Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
   
 0.973
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
   
 0.962
CNIH3
Cornichon family AMPA receptor auxiliary protein 3.
   
 0.960
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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