Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ESCO2Establishment of sister chromatid cohesion N-acetyltransferase 2. (600 aa)    
Predicted Functional Partners:
SMC3
Structural maintenance of chromosomes protein.
   
 0.954
PDS5A
PDS5 cohesin associated factor A.
   
 0.917
ESCO1
Establishment of sister chromatid cohesion N-acetyltransferase 1.
  
  
0.906
NUF2
NUF2 component of NDC80 kinetochore complex.
   
  
 0.870
RAD21
RAD21 cohesin complex component.
   
 0.866
PDS5B
PDS5 cohesin associated factor B.
   
 0.855
SMC1A
Structural maintenance of chromosomes protein.
   
 0.854
CHTF18
Chromosome transmission fidelity factor 18.
   
 
 0.853
KIF11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.846
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
  
 0.844
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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