| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BMP1 | C1R | ENSNLEP00000038034 | ENSNLEP00000023825 | Metalloendopeptidase. | CUB domain-containing protein. | 0.744 |
| BMP1 | C1S | ENSNLEP00000038034 | ENSNLEP00000006221 | Metalloendopeptidase. | Complement C1s; Belongs to the peptidase S1 family. | 0.648 |
| BMP1 | SCARA5 | ENSNLEP00000038034 | ENSNLEP00000020089 | Metalloendopeptidase. | Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the de [...] | 0.647 |
| C1R | BMP1 | ENSNLEP00000023825 | ENSNLEP00000038034 | CUB domain-containing protein. | Metalloendopeptidase. | 0.744 |
| C1R | C1S | ENSNLEP00000023825 | ENSNLEP00000006221 | CUB domain-containing protein. | Complement C1s; Belongs to the peptidase S1 family. | 0.999 |
| C1R | SCARA5 | ENSNLEP00000023825 | ENSNLEP00000020089 | CUB domain-containing protein. | Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the de [...] | 0.606 |
| C1R | SFTPD | ENSNLEP00000023825 | ENSNLEP00000012978 | CUB domain-containing protein. | Surfactant protein D. | 0.555 |
| C1S | BMP1 | ENSNLEP00000006221 | ENSNLEP00000038034 | Complement C1s; Belongs to the peptidase S1 family. | Metalloendopeptidase. | 0.648 |
| C1S | C1R | ENSNLEP00000006221 | ENSNLEP00000023825 | Complement C1s; Belongs to the peptidase S1 family. | CUB domain-containing protein. | 0.999 |
| C1S | SCARA5 | ENSNLEP00000006221 | ENSNLEP00000020089 | Complement C1s; Belongs to the peptidase S1 family. | Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the de [...] | 0.682 |
| C1S | SFTPD | ENSNLEP00000006221 | ENSNLEP00000012978 | Complement C1s; Belongs to the peptidase S1 family. | Surfactant protein D. | 0.598 |
| CALR | SCARA5 | ENSNLEP00000015731 | ENSNLEP00000020089 | Calreticulin. | Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the de [...] | 0.453 |
| CALR | SFTPD | ENSNLEP00000015731 | ENSNLEP00000012978 | Calreticulin. | Surfactant protein D. | 0.681 |
| CALR3 | SCARA5 | ENSNLEP00000006672 | ENSNLEP00000020089 | Calreticulin. | Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the de [...] | 0.412 |
| CD5 | SCARA5 | ENSNLEP00000002369 | ENSNLEP00000020089 | Uncharacterized protein. | Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the de [...] | 0.577 |
| FTL | SCARA5 | ENSNLEP00000043675 | ENSNLEP00000020089 | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. | Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the de [...] | 0.458 |
| PTK7 | SCARA5 | ENSNLEP00000005271 | ENSNLEP00000020089 | Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. | Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the de [...] | 0.404 |
| SCARA3 | SCARA5 | ENSNLEP00000020018 | ENSNLEP00000020089 | Scavenger receptor class A member 3. | Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the de [...] | 0.405 |
| SCARA5 | BMP1 | ENSNLEP00000020089 | ENSNLEP00000038034 | Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the de [...] | Metalloendopeptidase. | 0.647 |
| SCARA5 | C1R | ENSNLEP00000020089 | ENSNLEP00000023825 | Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the de [...] | CUB domain-containing protein. | 0.606 |