Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FAXDC2Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. (310 aa)    
Predicted Functional Partners:
CYP51A1
Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 0.942
SC5D
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 
 0.940
SQLE
Squalene epoxidase.
   
 
 0.913
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
   
 0.845
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 
 0.800
SIGMAR1
Sigma non-opioid intracellular receptor 1.
   
 0.782
NSDHL
NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family.
   
 0.778
TM7SF2
Transmembrane 7 superfamily member 2.
   
 0.768
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
  
 
 0.762
FA2H
Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]
   
 
 0.761
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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