STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK1Non-specific serine/threonine protein kinase. (545 aa)    
Predicted Functional Partners:
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.999
CDC42
Cell division cycle 42.
   
 0.999
NCK1
Cytoplasmic protein.
    
 0.996
NCK2
Cytoplasmic protein.
    
 0.992
PAK2
Non-specific serine/threonine protein kinase.
  
 
0.990
RAC2
Rac family small GTPase 2.
   
 0.969
FLNA
Filamin A.
    
 0.966
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.958
LIMK2
LIM domain kinase 2.
    
0.954
RAC1
Rac family small GTPase 1.
   
 0.948
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.