STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABCG8ATP binding cassette subfamily G member 8. (673 aa)    
Predicted Functional Partners:
ABCG5
ATP binding cassette subfamily G member 5.
  
0.999
NR1H3
Nuclear receptor subfamily 1 group H member 3.
   
 0.731
CYP7A1
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
   
 
 0.714
NPC1L1
NPC1 like intracellular cholesterol transporter 1.
   
 
 0.704
SREBF2
Sterol regulatory element binding transcription factor 2.
    
 
 0.701
NR1H2
Nuclear receptor subfamily 1 group H member 2.
   
 0.698
XPR1
Xenotropic and polytropic retrovirus receptor 1.
   
  
 0.696
UPP1
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
   
  
 0.695
NR1H4
Nuclear receptor subfamily 1 group H member 4.
   
 0.692
TBX22
T-box transcription factor 22.
      
 0.683
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: medium (68%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.