Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EPAS1Endothelial PAS domain protein 1. (869 aa)    
Predicted Functional Partners:
ARNT
Aryl hydrocarbon receptor nuclear translocator.
   
0.998
EGLN1
Egl-9 family hypoxia inducible factor 1.
    
 0.997
ARNT2
Uncharacterized protein.
   
0.992
EGLN3
Egl-9 family hypoxia inducible factor 3.
    
 0.991
EGLN2
Egl-9 family hypoxia inducible factor 2.
    
 0.991
HIF1A
Hypoxia inducible factor 1 subunit alpha.
   
0.991
EP300
E1A binding protein p300.
    
 0.990
VHL
Von Hippel-Lindau tumor suppressor.
    
 0.981
CREBBP
CREB binding protein.
   
 0.978
LOC100581166
Skp1_POZ domain-containing protein; Belongs to the SKP1 family.
    
 0.974
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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