| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APLF | APTX | ENSNLEP00000012214 | ENSNLEP00000049274 | Aprataxin and PNKP like factor. | Aprataxin. | 0.694 |
| APLF | LIG3 | ENSNLEP00000012214 | ENSNLEP00000035608 | Aprataxin and PNKP like factor. | DNA ligase. | 0.967 |
| APLF | PNKP | ENSNLEP00000012214 | ENSNLEP00000033964 | Aprataxin and PNKP like factor. | FHA_2 domain-containing protein. | 0.651 |
| APLF | POLB | ENSNLEP00000012214 | ENSNLEP00000015641 | Aprataxin and PNKP like factor. | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. | 0.935 |
| APLF | TDP1 | ENSNLEP00000012214 | ENSNLEP00000040013 | Aprataxin and PNKP like factor. | Tyrosyl-DNA phosphodiesterase 1. | 0.904 |
| APLF | TOP1 | ENSNLEP00000012214 | ENSNLEP00000007880 | Aprataxin and PNKP like factor. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.406 |
| APLF | XRCC1 | ENSNLEP00000012214 | ENSNLEP00000001912 | Aprataxin and PNKP like factor. | X-ray repair cross complementing 1. | 0.968 |
| APLF | XRCC5 | ENSNLEP00000012214 | ENSNLEP00000008862 | Aprataxin and PNKP like factor. | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. | 0.948 |
| APTX | APLF | ENSNLEP00000049274 | ENSNLEP00000012214 | Aprataxin. | Aprataxin and PNKP like factor. | 0.694 |
| APTX | LIG3 | ENSNLEP00000049274 | ENSNLEP00000035608 | Aprataxin. | DNA ligase. | 0.783 |
| APTX | PNKP | ENSNLEP00000049274 | ENSNLEP00000033964 | Aprataxin. | FHA_2 domain-containing protein. | 0.588 |
| APTX | POLB | ENSNLEP00000049274 | ENSNLEP00000015641 | Aprataxin. | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. | 0.645 |
| APTX | TDP1 | ENSNLEP00000049274 | ENSNLEP00000040013 | Aprataxin. | Tyrosyl-DNA phosphodiesterase 1. | 0.842 |
| APTX | XRCC1 | ENSNLEP00000049274 | ENSNLEP00000001912 | Aprataxin. | X-ray repair cross complementing 1. | 0.945 |
| APTX | XRCC5 | ENSNLEP00000049274 | ENSNLEP00000008862 | Aprataxin. | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. | 0.483 |
| ERCC4 | TDP1 | ENSNLEP00000012458 | ENSNLEP00000040013 | ERCC excision repair 4, endonuclease catalytic subunit. | Tyrosyl-DNA phosphodiesterase 1. | 0.780 |
| ERCC4 | TOP1 | ENSNLEP00000012458 | ENSNLEP00000007880 | ERCC excision repair 4, endonuclease catalytic subunit. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.437 |
| ERCC4 | TOP1MT | ENSNLEP00000012458 | ENSNLEP00000001974 | ERCC excision repair 4, endonuclease catalytic subunit. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.437 |
| ERCC4 | XRCC1 | ENSNLEP00000012458 | ENSNLEP00000001912 | ERCC excision repair 4, endonuclease catalytic subunit. | X-ray repair cross complementing 1. | 0.616 |
| LIG3 | APLF | ENSNLEP00000035608 | ENSNLEP00000012214 | DNA ligase. | Aprataxin and PNKP like factor. | 0.967 |
