C12orf66 protein (Nomascus leucogenys) - STRING interaction network

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Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMT2	C12orf66	ENSNLEP00000013825	ENSNLEP00000020737	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Chromosome 12 open reading frame 66.	0.955
BMT2	DEPDC5	ENSNLEP00000013825	ENSNLEP00000005768	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	DEP domain-containing protein.	0.953
BMT2	ENSNLEP00000033843	ENSNLEP00000013825	ENSNLEP00000033843	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Uncharacterized protein.	0.950
BMT2	KPTN	ENSNLEP00000013825	ENSNLEP00000003752	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Kaptin, actin binding protein.	0.911
BMT2	NPRL2	ENSNLEP00000013825	ENSNLEP00000008544	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	NPR2 like, GATOR1 complex subunit.	0.861
BMT2	NPRL3	ENSNLEP00000013825	ENSNLEP00000009719	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	NPR3 like, GATOR1 complex subunit.	0.891
BMT2	WDR59	ENSNLEP00000013825	ENSNLEP00000015758	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	WD repeat domain 59.	0.406
C12orf66	BMT2	ENSNLEP00000020737	ENSNLEP00000013825	Chromosome 12 open reading frame 66.	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	0.955
C12orf66	DEPDC5	ENSNLEP00000020737	ENSNLEP00000005768	Chromosome 12 open reading frame 66.	DEP domain-containing protein.	0.984
C12orf66	ENSNLEP00000033843	ENSNLEP00000020737	ENSNLEP00000033843	Chromosome 12 open reading frame 66.	Uncharacterized protein.	0.998
C12orf66	KPTN	ENSNLEP00000020737	ENSNLEP00000003752	Chromosome 12 open reading frame 66.	Kaptin, actin binding protein.	0.996
C12orf66	NPRL2	ENSNLEP00000020737	ENSNLEP00000008544	Chromosome 12 open reading frame 66.	NPR2 like, GATOR1 complex subunit.	0.978
C12orf66	NPRL3	ENSNLEP00000020737	ENSNLEP00000009719	Chromosome 12 open reading frame 66.	NPR3 like, GATOR1 complex subunit.	0.900
C12orf66	PPP1R3A	ENSNLEP00000020737	ENSNLEP00000013843	Chromosome 12 open reading frame 66.	Protein phosphatase 1 regulatory subunit 3A.	0.851
C12orf66	SZT2	ENSNLEP00000020737	ENSNLEP00000024360	Chromosome 12 open reading frame 66.	SZT2 subunit of KICSTOR complex.	0.908
C12orf66	WDR24	ENSNLEP00000020737	ENSNLEP00000025805	Chromosome 12 open reading frame 66.	WD repeat domain 24.	0.991
C12orf66	WDR59	ENSNLEP00000020737	ENSNLEP00000015758	Chromosome 12 open reading frame 66.	WD repeat domain 59.	0.982
DEPDC5	BMT2	ENSNLEP00000005768	ENSNLEP00000013825	DEP domain-containing protein.	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	0.953
DEPDC5	C12orf66	ENSNLEP00000005768	ENSNLEP00000020737	DEP domain-containing protein.	Chromosome 12 open reading frame 66.	0.984
DEPDC5	ENSNLEP00000033843	ENSNLEP00000005768	ENSNLEP00000033843	DEP domain-containing protein.	Uncharacterized protein.	0.979

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