node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACOX1 | ADIPOQ | ENSNLEP00000033574 | ENSNLEP00000008120 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Adiponectin, C1Q and collagen domain containing. | 0.529 |
ACOX1 | GPAT4 | ENSNLEP00000033574 | ENSNLEP00000034535 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Glycerol-3-phosphate acyltransferase 4. | 0.690 |
ACOX1 | PPARA | ENSNLEP00000033574 | ENSNLEP00000019094 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Peroxisome proliferator activated receptor alpha. | 0.821 |
ACOX1 | PPARG | ENSNLEP00000033574 | ENSNLEP00000037002 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.555 |
ACOX1 | PPARGC1A | ENSNLEP00000033574 | ENSNLEP00000041737 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | PPARG coactivator 1 alpha. | 0.485 |
ACOX1 | SREBF1 | ENSNLEP00000033574 | ENSNLEP00000031265 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Sterol regulatory element binding transcription factor 1. | 0.670 |
ACOX1 | UCP2 | ENSNLEP00000033574 | ENSNLEP00000020744 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.638 |
ADIPOQ | ACOX1 | ENSNLEP00000008120 | ENSNLEP00000033574 | Adiponectin, C1Q and collagen domain containing. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.529 |
ADIPOQ | ADRB3 | ENSNLEP00000008120 | ENSNLEP00000022973 | Adiponectin, C1Q and collagen domain containing. | G_PROTEIN_RECEP_F1_2 domain-containing protein. | 0.650 |
ADIPOQ | GHRL | ENSNLEP00000008120 | ENSNLEP00000005413 | Adiponectin, C1Q and collagen domain containing. | Ghrelin and obestatin prepropeptide. | 0.661 |
ADIPOQ | LEP | ENSNLEP00000008120 | ENSNLEP00000014938 | Adiponectin, C1Q and collagen domain containing. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.930 |
ADIPOQ | PPARA | ENSNLEP00000008120 | ENSNLEP00000019094 | Adiponectin, C1Q and collagen domain containing. | Peroxisome proliferator activated receptor alpha. | 0.723 |
ADIPOQ | PPARG | ENSNLEP00000008120 | ENSNLEP00000037002 | Adiponectin, C1Q and collagen domain containing. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.797 |
ADIPOQ | PPARGC1A | ENSNLEP00000008120 | ENSNLEP00000041737 | Adiponectin, C1Q and collagen domain containing. | PPARG coactivator 1 alpha. | 0.771 |
ADIPOQ | SREBF1 | ENSNLEP00000008120 | ENSNLEP00000031265 | Adiponectin, C1Q and collagen domain containing. | Sterol regulatory element binding transcription factor 1. | 0.577 |
ADIPOQ | UCP2 | ENSNLEP00000008120 | ENSNLEP00000020744 | Adiponectin, C1Q and collagen domain containing. | Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.608 |
ADRB3 | ADIPOQ | ENSNLEP00000022973 | ENSNLEP00000008120 | G_PROTEIN_RECEP_F1_2 domain-containing protein. | Adiponectin, C1Q and collagen domain containing. | 0.650 |
ADRB3 | LEP | ENSNLEP00000022973 | ENSNLEP00000014938 | G_PROTEIN_RECEP_F1_2 domain-containing protein. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.593 |
ADRB3 | PPARA | ENSNLEP00000022973 | ENSNLEP00000019094 | G_PROTEIN_RECEP_F1_2 domain-containing protein. | Peroxisome proliferator activated receptor alpha. | 0.550 |
ADRB3 | PPARG | ENSNLEP00000022973 | ENSNLEP00000037002 | G_PROTEIN_RECEP_F1_2 domain-containing protein. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.512 |