Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)    
Predicted Functional Partners:
EIF2AK3
Eukaryotic translation initiation factor 2 alpha kinase 3.
   
 0.997
ATF6
Activating transcription factor 6.
    
 0.995
ERN1
Endoplasmic reticulum to nucleus signaling 1.
    
 0.995
HSP90B1
Heat shock protein 90 beta family member 1.
   
 0.983
HYOU1
Hypoxia up-regulated 1.
  
0.980
LOC100603153
Uncharacterized protein.
   
 0.975
PDIA3
Protein disulfide-isomerase.
   
 0.974
DNAJB11
J domain-containing protein.
 
 0.974
PDIA4
Protein disulfide-isomerase.
   
 0.973
PDIA6
Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family.
   
 0.972
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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