STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STAT6Signal transducer and activator of transcription. (842 aa)    
Predicted Functional Partners:
IL4R
Interleukin 4 receptor.
   
 0.995
EP300
E1A binding protein p300.
    
 0.992
JAK3
Tyrosine-protein kinase.
   
 0.989
CREBBP
CREB binding protein.
    
 0.989
JAK1
Tyrosine-protein kinase.
   
 0.987
JAK2
Tyrosine-protein kinase.
   
 0.985
STAT3
Signal transducer and activator of transcription.
   
0.985
STAT2
Signal transducer and activator of transcription.
  
0.976
IRF9
Interferon regulatory factor 9.
   
 0.968
PIAS2
Protein inhibitor of activated STAT 2.
    
 0.960
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.