Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PTGES2Prostaglandin E synthase 2. (377 aa)    
Predicted Functional Partners:
PTGES
Prostaglandin E synthase.
     
 0.961
PTGES3
Prostaglandin E synthase 3.
     
 0.961
PTGS2
Prostaglandin-endoperoxide synthase 2.
     
 0.944
ENSNLEP00000030863
CS domain-containing protein.
     
 0.943
PTGS1
Prostaglandin-endoperoxide synthase 1.
     
 0.943
TBXAS1
Thromboxane A synthase 1; Belongs to the cytochrome P450 family.
     
 0.934
HPGD
15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.928
PTGIS
Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family.
     
 0.928
HPGDS
Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily.
     
 0.927
PTGDS
Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family.
     
 0.926
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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