Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1038 aa)    
Predicted Functional Partners:
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.999
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
   
 0.991
FN1
Fibronectin 1.
    
 0.972
ITGB2
Integrin beta.
   
 0.962
ITGB7
Integrin beta; Belongs to the integrin beta chain family.
   
 0.962
PTK2B
Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.960
TLN1
Talin 1.
   
 0.956
PXN
Uncharacterized protein.
   
 0.950
ITGA4
Integrin subunit alpha 4; Belongs to the integrin alpha chain family.
    
0.944
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
   
 0.939
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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