STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (329 aa)    
Predicted Functional Partners:
NTRK2
Tyrosine-protein kinase receptor.
   
 0.999
NTRK1
Tyrosine-protein kinase receptor.
   
 0.992
NTRK3
Tyrosine-protein kinase receptor.
   
 0.979
NTF4
Neurotrophin 4; Belongs to the NGF-beta family.
    
0.973
SORT1
Sortilin.
    
 
 0.962
G1QS07_NOMLE
Uncharacterized protein.
    
 0.937
MECP2
MBD domain-containing protein.
    
 0.870
GDNF
TGF_BETA_2 domain-containing protein.
      
 0.836
EGFR
Receptor protein-tyrosine kinase.
     
 0.803
FGFR1
Fibroblast growth factor receptor.
     
 0.802
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.