Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTPRCProtein tyrosine phosphatase receptor type C. (1304 aa)    
Predicted Functional Partners:
HCK
Tyrosine-protein kinase.
   
 0.986
SEMA4D
Semaphorin 4D; Belongs to the semaphorin family.
    
 0.975
LCK
LCK proto-oncogene, Src family tyrosine kinase.
   
 0.973
LYN
Tyrosine-protein kinase.
   
 0.966
FYN
Tyrosine-protein kinase.
   
 0.966
ITGB2
Integrin beta.
   
 0.905
LCP2
Lymphocyte cytosolic protein 2.
   
 
 0.902
CD53
Tetraspanin.
   
 0.857
ITGAM
Integrin subunit alpha M; Belongs to the integrin alpha chain family.
   
 0.849
DOCK2
Dedicator of cytokinesis 2; Belongs to the DOCK family.
   
 
 0.848
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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