STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRY3Sprouty RTK signaling antagonist 3. (288 aa)    
Predicted Functional Partners:
CBLB
Uncharacterized protein.
    
 0.692
CBL
Cbl proto-oncogene.
    
 0.692
CBLC
Cbl proto-oncogene C.
    
 0.692
SPRY1
Sprouty RTK signaling antagonist 1.
   
0.591
VAMP7
Vesicle associated membrane protein 7; Belongs to the synaptobrevin family.
      
 0.587
IL9R
Interleukin 9 receptor.
      
 0.573
GRAP
SH3 domain-containing protein.
    
 0.536
GRAP2
GRB2 related adaptor protein 2.
    
 0.536
GRB2
Growth factor receptor bound protein 2.
    
 0.536
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 0.514
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.