| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GRB2 | INS-IGF2 | ENSNLEP00000040743 | ENSNLEP00000016293 | Growth factor receptor bound protein 2. | INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.648 |
| GRB2 | IRS1 | ENSNLEP00000040743 | ENSNLEP00000035157 | Growth factor receptor bound protein 2. | Insulin receptor substrate 1. | 0.998 |
| GRB2 | IRS2 | ENSNLEP00000040743 | ENSNLEP00000046467 | Growth factor receptor bound protein 2. | Insulin receptor substrate 2. | 0.994 |
| GRB2 | IRS4 | ENSNLEP00000040743 | ENSNLEP00000022231 | Growth factor receptor bound protein 2. | Insulin receptor substrate 4. | 0.987 |
| GRB2 | JAK2 | ENSNLEP00000040743 | ENSNLEP00000010932 | Growth factor receptor bound protein 2. | Tyrosine-protein kinase. | 0.916 |
| GRB2 | PIK3CA | ENSNLEP00000040743 | ENSNLEP00000006936 | Growth factor receptor bound protein 2. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.859 |
| GRB2 | PIK3CB | ENSNLEP00000040743 | ENSNLEP00000005291 | Growth factor receptor bound protein 2. | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. | 0.612 |
| GRB2 | PIK3R1 | ENSNLEP00000040743 | ENSNLEP00000031935 | Growth factor receptor bound protein 2. | Phosphoinositide-3-kinase regulatory subunit 1. | 0.986 |
| GRB2 | PIK3R2 | ENSNLEP00000040743 | ENSNLEP00000007175 | Growth factor receptor bound protein 2. | Uncharacterized protein. | 0.746 |
| GRB2 | PIK3R3 | ENSNLEP00000040743 | ENSNLEP00000045443 | Growth factor receptor bound protein 2. | Phosphoinositide-3-kinase regulatory subunit 3. | 0.746 |
| INS-IGF2 | GRB2 | ENSNLEP00000016293 | ENSNLEP00000040743 | INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Growth factor receptor bound protein 2. | 0.648 |
| INS-IGF2 | IRS1 | ENSNLEP00000016293 | ENSNLEP00000035157 | INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Insulin receptor substrate 1. | 0.959 |
| INS-IGF2 | IRS2 | ENSNLEP00000016293 | ENSNLEP00000046467 | INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Insulin receptor substrate 2. | 0.970 |
| INS-IGF2 | IRS4 | ENSNLEP00000016293 | ENSNLEP00000022231 | INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Insulin receptor substrate 4. | 0.959 |
| INS-IGF2 | JAK2 | ENSNLEP00000016293 | ENSNLEP00000010932 | INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Tyrosine-protein kinase. | 0.414 |
| IRS1 | GRB2 | ENSNLEP00000035157 | ENSNLEP00000040743 | Insulin receptor substrate 1. | Growth factor receptor bound protein 2. | 0.998 |
| IRS1 | INS-IGF2 | ENSNLEP00000035157 | ENSNLEP00000016293 | Insulin receptor substrate 1. | INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.959 |
| IRS1 | IRS2 | ENSNLEP00000035157 | ENSNLEP00000046467 | Insulin receptor substrate 1. | Insulin receptor substrate 2. | 0.997 |
| IRS1 | IRS4 | ENSNLEP00000035157 | ENSNLEP00000022231 | Insulin receptor substrate 1. | Insulin receptor substrate 4. | 0.972 |
| IRS1 | JAK2 | ENSNLEP00000035157 | ENSNLEP00000010932 | Insulin receptor substrate 1. | Tyrosine-protein kinase. | 0.990 |