Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TNP2Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. (143 aa)    
Predicted Functional Partners:
TNP1
Transition protein 1.
   
  
 0.860
VWF
Von Willebrand factor.
     
 0.856
MSH4
MutS homolog 4.
      
 0.810
ENSNLEP00000031105
Uncharacterized protein.
   
  
 0.791
OR5AN1
Olfactory receptor.
      
 0.790
PLAUR
Plasminogen activator, urokinase receptor.
   
  
 0.737
DMRT1
Doublesex and mab-3 related transcription factor 1.
      
 0.660
SFMBT1
Scm like with four mbt domains 1.
      
 0.655
PBK
PDZ binding kinase.
   
 0.647
ASF1B
Anti-silencing function 1B histone chaperone.
      
 0.642
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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