STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNP2Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. (143 aa)    
Predicted Functional Partners:
TNP1
Transition protein 1.
   
  
 0.909
MSH4
MutS homolog 4.
      
 0.847
ENSNLEP00000031105
Uncharacterized protein.
   
  
 0.818
DMRT1
Doublesex and mab-3 related transcription factor 1.
      
 0.728
PLAUR
Plasminogen activator, urokinase receptor.
   
  
 0.674
OR5AN1
Olfactory receptor.
      
 0.662
VWF
Von Willebrand factor.
   
 
 0.635
CUL5
Cullin 5; Belongs to the cullin family.
   
 0.616
KPNA3
Importin subunit alpha; Functions in nuclear protein import.
      
 0.586
BCL2
BCL2 apoptosis regulator.
   
 
 0.584
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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