Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CDK5R2Cyclin-dependent kinase 5 activator. (367 aa)    
Predicted Functional Partners:
CDK5
Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.
    
 0.982
ENSNLEP00000036861
Uncharacterized protein.
    
 0.973
CRMP1
Collapsin response mediator protein 1.
   
 
 0.777
LRCH1
Leucine rich repeats and calponin homology domain containing 1.
      
 0.644
DPYSL4
Dihydropyrimidinase like 4.
   
 
 0.631
NRP1
Neuropilin; Belongs to the neuropilin family.
     
 0.630
G1R9J5_NOMLE
SAM domain-containing protein.
    
 0.600
TP63
Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
    
 0.572
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
    
 
 0.570
JUN
BZIP domain-containing protein; Belongs to the bZIP family.
    
 0.566
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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