Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SOX2SRY-box transcription factor 2. (319 aa)    
Predicted Functional Partners:
POU5F1
POU domain protein.
    
 0.960
ENSNLEP00000044747
Uncharacterized protein.
    
 0.948
NANOG
Homeobox domain-containing protein.
    
 0.943
G1QZW6_NOMLE
Homeobox domain-containing protein.
    
 0.912
CTNNB1
Catenin beta 1.
    
 0.911
KLF4
Uncharacterized protein.
    
 0.901
SALL4
Spalt like transcription factor 4.
   
 0.878
PRDM14
PR/SET domain 14.
    
 0.841
SOX14
SRY-box transcription factor 14.
   
 
 0.834
POU2F1
POU domain protein.
   
 0.821
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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