Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADRB1Adrenoceptor beta 1. (476 aa)    
Predicted Functional Partners:
ADRB3
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
 
 
0.987
GNAS
GNAS complex locus.
    
 0.976
GNAI2
G protein subunit alpha i2.
    
 0.939
GNAI1
G protein subunit alpha i1.
    
 0.936
GNAI3
G protein subunit alpha i3.
    
 0.936
USP33
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
    
 0.933
POMC
Proopiomelanocortin.
   
 0.925
GIP
Gastric inhibitory polypeptide.
     
 0.918
GCG
Glucagon.
     
 0.914
CRH
Corticotropin releasing hormone.
     
 0.914
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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