STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOK2Docking protein 2. (412 aa)    
Predicted Functional Partners:
RASA1
RAS p21 protein activator 1.
   
 
 0.828
LCK
LCK proto-oncogene, Src family tyrosine kinase.
   
 0.754
TEK
TEK receptor tyrosine kinase.
    
 0.740
NCK1
Cytoplasmic protein.
    
 
 0.727
IL2RG
Fibronectin type-III domain-containing protein.
   
  
 0.700
TIE1
Tyrosine kinase with immunoglobulin like and EGF like domains 1.
    
 0.667
CCND3
Uncharacterized protein; Belongs to the cyclin family.
   
  
 0.656
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
  0.643
GRB2
Growth factor receptor bound protein 2.
    
 0.630
GFRA2
Uncharacterized protein.
     
 0.627
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.