Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)    
Predicted Functional Partners:
MSH6
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
0.999
MLH1
MutL homolog 1.
 
 0.998
MSH3
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
0.998
EXO1
Exonuclease 1.
   
 0.990
PMS1
PMS1 homolog 1, mismatch repair system component.
 
 0.984
G1QJN0_NOMLE
Uncharacterized protein.
 
 0.980
LOC100597058
MutL_C domain-containing protein.
  
 0.971
SMARCAD1
Uncharacterized protein.
   
 
 0.946
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.945
BRCA1
BRCA1 DNA repair associated.
   
 0.935
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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