| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSNLEP00000027432 | ENSNLEP00000039390 | ENSNLEP00000027432 | ENSNLEP00000039390 | TNF receptor-associated factor. | Protein kinase domain-containing protein. | 0.980 |
| ENSNLEP00000027432 | IL1A | ENSNLEP00000027432 | ENSNLEP00000002245 | TNF receptor-associated factor. | Interleukin-1; Belongs to the IL-1 family. | 0.655 |
| ENSNLEP00000027432 | IL1B | ENSNLEP00000027432 | ENSNLEP00000044905 | TNF receptor-associated factor. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.664 |
| ENSNLEP00000027432 | IL1R1 | ENSNLEP00000027432 | ENSNLEP00000023655 | TNF receptor-associated factor. | Interleukin 1 receptor type 1. | 0.914 |
| ENSNLEP00000027432 | IL1RAP | ENSNLEP00000027432 | ENSNLEP00000048062 | TNF receptor-associated factor. | Interleukin 1 receptor accessory protein. | 0.539 |
| ENSNLEP00000027432 | IRAK4 | ENSNLEP00000027432 | ENSNLEP00000021784 | TNF receptor-associated factor. | Interleukin 1 receptor associated kinase 4. | 0.948 |
| ENSNLEP00000027432 | MYD88 | ENSNLEP00000027432 | ENSNLEP00000006463 | TNF receptor-associated factor. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. | 0.960 |
| ENSNLEP00000039390 | ENSNLEP00000027432 | ENSNLEP00000039390 | ENSNLEP00000027432 | Protein kinase domain-containing protein. | TNF receptor-associated factor. | 0.980 |
| ENSNLEP00000039390 | IL1A | ENSNLEP00000039390 | ENSNLEP00000002245 | Protein kinase domain-containing protein. | Interleukin-1; Belongs to the IL-1 family. | 0.762 |
| ENSNLEP00000039390 | IL1B | ENSNLEP00000039390 | ENSNLEP00000044905 | Protein kinase domain-containing protein. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.789 |
| ENSNLEP00000039390 | IL1R1 | ENSNLEP00000039390 | ENSNLEP00000023655 | Protein kinase domain-containing protein. | Interleukin 1 receptor type 1. | 0.982 |
| ENSNLEP00000039390 | IL1RAP | ENSNLEP00000039390 | ENSNLEP00000048062 | Protein kinase domain-containing protein. | Interleukin 1 receptor accessory protein. | 0.895 |
| ENSNLEP00000039390 | IRAK4 | ENSNLEP00000039390 | ENSNLEP00000021784 | Protein kinase domain-containing protein. | Interleukin 1 receptor associated kinase 4. | 0.996 |
| ENSNLEP00000039390 | MYD88 | ENSNLEP00000039390 | ENSNLEP00000006463 | Protein kinase domain-containing protein. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. | 0.991 |
| ENSNLEP00000039390 | TRAF6 | ENSNLEP00000039390 | ENSNLEP00000021805 | Protein kinase domain-containing protein. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.995 |
| IL1A | ENSNLEP00000027432 | ENSNLEP00000002245 | ENSNLEP00000027432 | Interleukin-1; Belongs to the IL-1 family. | TNF receptor-associated factor. | 0.655 |
| IL1A | ENSNLEP00000039390 | ENSNLEP00000002245 | ENSNLEP00000039390 | Interleukin-1; Belongs to the IL-1 family. | Protein kinase domain-containing protein. | 0.762 |
| IL1A | IL1B | ENSNLEP00000002245 | ENSNLEP00000044905 | Interleukin-1; Belongs to the IL-1 family. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.999 |
| IL1A | IL1R1 | ENSNLEP00000002245 | ENSNLEP00000023655 | Interleukin-1; Belongs to the IL-1 family. | Interleukin 1 receptor type 1. | 0.996 |
| IL1A | IL1R2 | ENSNLEP00000002245 | ENSNLEP00000017748 | Interleukin-1; Belongs to the IL-1 family. | Interleukin 1 receptor type 2. | 0.994 |
