| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGO2 | DDX17 | ENSNLEP00000001761 | ENSNLEP00000047207 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | 0.516 |
| AGO2 | DDX5 | ENSNLEP00000001761 | ENSNLEP00000044468 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | DEAD-box helicase 5; Belongs to the DEAD box helicase family. | 0.708 |
| AGO2 | DGCR8 | ENSNLEP00000001761 | ENSNLEP00000006865 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | DGCR8 microprocessor complex subunit. | 0.810 |
| AGO2 | DICER1 | ENSNLEP00000001761 | ENSNLEP00000021032 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | 0.998 |
| AGO2 | DROSHA | ENSNLEP00000001761 | ENSNLEP00000035479 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Drosha ribonuclease III. | 0.959 |
| AGO2 | HNRNPA2B1 | ENSNLEP00000001761 | ENSNLEP00000018157 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Heterogeneous nuclear ribonucleoprotein A2/B1. | 0.433 |
| AGO2 | MECP2 | ENSNLEP00000001761 | ENSNLEP00000036087 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | MBD domain-containing protein. | 0.401 |
| AGO2 | TARBP2 | ENSNLEP00000001761 | ENSNLEP00000021465 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] | 0.995 |
| DDX17 | AGO2 | ENSNLEP00000047207 | ENSNLEP00000001761 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.516 |
| DDX17 | DDX5 | ENSNLEP00000047207 | ENSNLEP00000044468 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | DEAD-box helicase 5; Belongs to the DEAD box helicase family. | 0.966 |
| DDX17 | DGCR8 | ENSNLEP00000047207 | ENSNLEP00000006865 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | DGCR8 microprocessor complex subunit. | 0.877 |
| DDX17 | DICER1 | ENSNLEP00000047207 | ENSNLEP00000021032 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | 0.439 |
| DDX17 | DROSHA | ENSNLEP00000047207 | ENSNLEP00000035479 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | Drosha ribonuclease III. | 0.922 |
| DDX5 | AGO2 | ENSNLEP00000044468 | ENSNLEP00000001761 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.708 |
| DDX5 | DDX17 | ENSNLEP00000044468 | ENSNLEP00000047207 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | 0.966 |
| DDX5 | DGCR8 | ENSNLEP00000044468 | ENSNLEP00000006865 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. | DGCR8 microprocessor complex subunit. | 0.844 |
| DDX5 | DICER1 | ENSNLEP00000044468 | ENSNLEP00000021032 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | 0.401 |
| DDX5 | DROSHA | ENSNLEP00000044468 | ENSNLEP00000035479 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. | Drosha ribonuclease III. | 0.995 |
| DDX5 | HNRNPA2B1 | ENSNLEP00000044468 | ENSNLEP00000018157 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. | Heterogeneous nuclear ribonucleoprotein A2/B1. | 0.663 |
| DDX5 | METTL3 | ENSNLEP00000044468 | ENSNLEP00000017753 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. | Methyltransferase like 3; Belongs to the MT-A70-like family. | 0.461 |