| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ERBB3 | GAB1 | ENSNLEP00000047229 | ENSNLEP00000006513 | Erb-b2 receptor tyrosine kinase 3. | GRB2 associated binding protein 1. | 0.978 |
| ERBB3 | HGF | ENSNLEP00000047229 | ENSNLEP00000023996 | Erb-b2 receptor tyrosine kinase 3. | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | 0.926 |
| ERBB3 | MET | ENSNLEP00000047229 | ENSNLEP00000024614 | Erb-b2 receptor tyrosine kinase 3. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.975 |
| ERBB3 | MST1R | ENSNLEP00000047229 | ENSNLEP00000008444 | Erb-b2 receptor tyrosine kinase 3. | Macrophage stimulating 1 receptor. | 0.727 |
| ERBB3 | PIK3CA | ENSNLEP00000047229 | ENSNLEP00000006936 | Erb-b2 receptor tyrosine kinase 3. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.992 |
| ERBB3 | STAT3 | ENSNLEP00000047229 | ENSNLEP00000014018 | Erb-b2 receptor tyrosine kinase 3. | Signal transducer and activator of transcription. | 0.757 |
| GAB1 | ERBB3 | ENSNLEP00000006513 | ENSNLEP00000047229 | GRB2 associated binding protein 1. | Erb-b2 receptor tyrosine kinase 3. | 0.978 |
| GAB1 | HGF | ENSNLEP00000006513 | ENSNLEP00000023996 | GRB2 associated binding protein 1. | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | 0.875 |
| GAB1 | MET | ENSNLEP00000006513 | ENSNLEP00000024614 | GRB2 associated binding protein 1. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.991 |
| GAB1 | MST1R | ENSNLEP00000006513 | ENSNLEP00000008444 | GRB2 associated binding protein 1. | Macrophage stimulating 1 receptor. | 0.889 |
| GAB1 | PIK3CA | ENSNLEP00000006513 | ENSNLEP00000006936 | GRB2 associated binding protein 1. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.980 |
| HGF | ERBB3 | ENSNLEP00000023996 | ENSNLEP00000047229 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Erb-b2 receptor tyrosine kinase 3. | 0.926 |
| HGF | GAB1 | ENSNLEP00000023996 | ENSNLEP00000006513 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | GRB2 associated binding protein 1. | 0.875 |
| HGF | HPN | ENSNLEP00000023996 | ENSNLEP00000032095 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Hepsin; Belongs to the peptidase S1 family. | 0.883 |
| HGF | IL7 | ENSNLEP00000023996 | ENSNLEP00000041342 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Interleukin 7. | 0.834 |
| HGF | MET | ENSNLEP00000023996 | ENSNLEP00000024614 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.999 |
| HGF | MST1R | ENSNLEP00000023996 | ENSNLEP00000008444 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Macrophage stimulating 1 receptor. | 0.961 |
| HGF | PIK3CA | ENSNLEP00000023996 | ENSNLEP00000006936 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.845 |
| HGF | SPINT1 | ENSNLEP00000023996 | ENSNLEP00000029153 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Serine peptidase inhibitor, Kunitz type 1. | 0.937 |
| HGF | SPINT2 | ENSNLEP00000023996 | ENSNLEP00000020563 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Serine peptidase inhibitor, Kunitz type 2. | 0.910 |