STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL6STInterleukin 6 signal transducer. (918 aa)    
Predicted Functional Partners:
IL6
Uncharacterized protein.
    
 0.968
JAK1
Tyrosine-protein kinase.
   
 0.967
LIF
LIF interleukin 6 family cytokine.
    
 0.966
JAK2
Tyrosine-protein kinase.
   
 0.961
OSM
Oncostatin M.
    
 0.956
IL11
Uncharacterized protein.
    
 0.950
CNTF
Ciliary neurotrophic factor.
    
 0.949
STAT3
Signal transducer and activator of transcription.
   
 0.944
LIFR
LIF receptor subunit alpha.
   
0.944
CTF1
Cardiotrophin 1.
     
 0.939
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.