Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HADHHydroxyacyl-CoA dehydrogenase. (390 aa)    
Predicted Functional Partners:
ECHS1
Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.
 0.999
HADHB
Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.994
ACAT1
Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.990
ACAA2
Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.990
ACAT2
Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.981
HSD17B10
Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.973
OXCT1
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 
 0.972
OXCT2
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 
 0.972
HADHA
Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.
  
0.960
EHHADH
Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
0.960
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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