node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COQ2 | ENSNLEP00000039238 | ENSNLEP00000011010 | ENSNLEP00000039238 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Nudix hydrolase domain-containing protein. | 0.788 |
COQ2 | FDFT1 | ENSNLEP00000011010 | ENSNLEP00000018325 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Farnesyl-diphosphate farnesyltransferase 1. | 0.615 |
COQ2 | IDI1 | ENSNLEP00000011010 | ENSNLEP00000026665 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Nudix hydrolase domain-containing protein. | 0.788 |
COQ2 | IDI2 | ENSNLEP00000011010 | ENSNLEP00000016453 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Isopentenyl-diphosphate delta isomerase 2. | 0.788 |
COQ2 | LOC100590882 | ENSNLEP00000011010 | ENSNLEP00000027791 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. | 0.587 |
COQ2 | LSS | ENSNLEP00000011010 | ENSNLEP00000003484 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.710 |
COQ2 | MVD | ENSNLEP00000011010 | ENSNLEP00000000682 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.416 |
COQ2 | NDUFAF6 | ENSNLEP00000011010 | ENSNLEP00000004292 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | NADH:ubiquinone oxidoreductase complex assembly factor 6. | 0.601 |
ENSNLEP00000039238 | COQ2 | ENSNLEP00000039238 | ENSNLEP00000011010 | Nudix hydrolase domain-containing protein. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.788 |
ENSNLEP00000039238 | FDFT1 | ENSNLEP00000039238 | ENSNLEP00000018325 | Nudix hydrolase domain-containing protein. | Farnesyl-diphosphate farnesyltransferase 1. | 0.677 |
ENSNLEP00000039238 | HMGCS1 | ENSNLEP00000039238 | ENSNLEP00000032370 | Nudix hydrolase domain-containing protein. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.841 |
ENSNLEP00000039238 | HMGCS2 | ENSNLEP00000039238 | ENSNLEP00000047154 | Nudix hydrolase domain-containing protein. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.685 |
ENSNLEP00000039238 | LOC100590882 | ENSNLEP00000039238 | ENSNLEP00000027791 | Nudix hydrolase domain-containing protein. | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. | 0.599 |
ENSNLEP00000039238 | LSS | ENSNLEP00000039238 | ENSNLEP00000003484 | Nudix hydrolase domain-containing protein. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.870 |
ENSNLEP00000039238 | MVD | ENSNLEP00000039238 | ENSNLEP00000000682 | Nudix hydrolase domain-containing protein. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.892 |
ENSNLEP00000039238 | NDUFAF6 | ENSNLEP00000039238 | ENSNLEP00000004292 | Nudix hydrolase domain-containing protein. | NADH:ubiquinone oxidoreductase complex assembly factor 6. | 0.457 |
FDFT1 | COQ2 | ENSNLEP00000018325 | ENSNLEP00000011010 | Farnesyl-diphosphate farnesyltransferase 1. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.615 |
FDFT1 | ENSNLEP00000039238 | ENSNLEP00000018325 | ENSNLEP00000039238 | Farnesyl-diphosphate farnesyltransferase 1. | Nudix hydrolase domain-containing protein. | 0.677 |
FDFT1 | HMGCS1 | ENSNLEP00000018325 | ENSNLEP00000032370 | Farnesyl-diphosphate farnesyltransferase 1. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.925 |
FDFT1 | HMGCS2 | ENSNLEP00000018325 | ENSNLEP00000047154 | Farnesyl-diphosphate farnesyltransferase 1. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.916 |