Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CACYBPUncharacterized protein. (226 aa)    
Predicted Functional Partners:
SIAH1
E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
    
 0.982
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
   
 0.961
S100A6
Protein S100; Belongs to the S-100 family.
    
 
 0.802
CTNNB1
Catenin beta 1.
   
 
 0.760
RNF41
Ring finger protein 41.
    
 
 0.723
SIAH2
E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
    
 
 0.641
ENSNLEP00000029811
Uncharacterized protein; Belongs to the SKP1 family.
   
 
 0.634
ENSNLEP00000042252
Uncharacterized protein; Belongs to the SKP1 family.
   
 
 0.612
TBL1X
Transducin beta like 1 X-linked.
    
   0.582
AHSA1
Activator of HSP90 ATPase activity 1.
   
 
 0.573
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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