| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADK | ADSS1 | ENSNLEP00000027277 | ENSNLEP00000019807 | Adenosine kinase. | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.561 |
| ADK | AK3 | ENSNLEP00000027277 | ENSNLEP00000010830 | Adenosine kinase. | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 0.940 |
| ADK | AMPD1 | ENSNLEP00000027277 | ENSNLEP00000030658 | Adenosine kinase. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.958 |
| ADK | AMPD2 | ENSNLEP00000027277 | ENSNLEP00000003812 | Adenosine kinase. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.960 |
| ADK | AMPD3 | ENSNLEP00000027277 | ENSNLEP00000048670 | Adenosine kinase. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.954 |
| ADK | APRT | ENSNLEP00000027277 | ENSNLEP00000018947 | Adenosine kinase. | Adenine phosphoribosyltransferase. | 0.987 |
| ADK | ATIC | ENSNLEP00000027277 | ENSNLEP00000008808 | Adenosine kinase. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.637 |
| ADK | HPRT1 | ENSNLEP00000027277 | ENSNLEP00000002427 | Adenosine kinase. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.464 |
| ADK | NT5C | ENSNLEP00000027277 | ENSNLEP00000000697 | Adenosine kinase. | 5', 3'-nucleotidase, cytosolic. | 0.909 |
| ADK | NT5E | ENSNLEP00000027277 | ENSNLEP00000015555 | Adenosine kinase. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.938 |
| ADSS1 | ADK | ENSNLEP00000019807 | ENSNLEP00000027277 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenosine kinase. | 0.561 |
| ADSS1 | AMPD1 | ENSNLEP00000019807 | ENSNLEP00000030658 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.951 |
| ADSS1 | AMPD2 | ENSNLEP00000019807 | ENSNLEP00000003812 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.936 |
| ADSS1 | AMPD3 | ENSNLEP00000019807 | ENSNLEP00000048670 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.936 |
| ADSS1 | APRT | ENSNLEP00000019807 | ENSNLEP00000018947 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Adenine phosphoribosyltransferase. | 0.724 |
| ADSS1 | ATIC | ENSNLEP00000019807 | ENSNLEP00000008808 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | 0.991 |
| ADSS1 | HPRT1 | ENSNLEP00000019807 | ENSNLEP00000002427 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.936 |
| ADSS1 | NT5C | ENSNLEP00000019807 | ENSNLEP00000000697 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 5', 3'-nucleotidase, cytosolic. | 0.907 |
| ADSS1 | NT5E | ENSNLEP00000019807 | ENSNLEP00000015555 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. | 0.922 |
| AK3 | ADK | ENSNLEP00000010830 | ENSNLEP00000027277 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | Adenosine kinase. | 0.940 |
