LOC100588616 protein (Nomascus leucogenys) - STRING interaction network

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Score

LOC100588616

Runt domain-containing protein. (504 aa)

Predicted Functional Partners:

CBFB

0.991

EP300

0.928

HDAC4

0.906

SOX9

0.905

ZFHX3

0.882

BGLAP

0.878

RUNX3

0.878

SMAD1

0.873

SMAD3

0.862

YAP1

0.854

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BGLAP	CBFB	ENSNLEP00000030826	ENSNLEP00000005199	Osteocalcin; Binds strongly to apatite and calcium.	Core-binding factor subunit beta.	0.518
BGLAP	LOC100588616	ENSNLEP00000030826	ENSNLEP00000031531	Osteocalcin; Binds strongly to apatite and calcium.	Runt domain-containing protein.	0.878
BGLAP	RUNX3	ENSNLEP00000030826	ENSNLEP00000046876	Osteocalcin; Binds strongly to apatite and calcium.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.732
BGLAP	SOX9	ENSNLEP00000030826	ENSNLEP00000027248	Osteocalcin; Binds strongly to apatite and calcium.	SRY-box transcription factor 9.	0.468
CBFB	BGLAP	ENSNLEP00000005199	ENSNLEP00000030826	Core-binding factor subunit beta.	Osteocalcin; Binds strongly to apatite and calcium.	0.518
CBFB	EP300	ENSNLEP00000005199	ENSNLEP00000035934	Core-binding factor subunit beta.	E1A binding protein p300.	0.564
CBFB	HDAC4	ENSNLEP00000005199	ENSNLEP00000016326	Core-binding factor subunit beta.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.455
CBFB	LOC100588616	ENSNLEP00000005199	ENSNLEP00000031531	Core-binding factor subunit beta.	Runt domain-containing protein.	0.991
CBFB	RUNX3	ENSNLEP00000005199	ENSNLEP00000046876	Core-binding factor subunit beta.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.992
CBFB	SMAD1	ENSNLEP00000005199	ENSNLEP00000006702	Core-binding factor subunit beta.	Mothers against decapentaplegic homolog.	0.496
CBFB	YAP1	ENSNLEP00000005199	ENSNLEP00000031727	Core-binding factor subunit beta.	Uncharacterized protein.	0.498
EP300	CBFB	ENSNLEP00000035934	ENSNLEP00000005199	E1A binding protein p300.	Core-binding factor subunit beta.	0.564
EP300	HDAC4	ENSNLEP00000035934	ENSNLEP00000016326	E1A binding protein p300.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.655
EP300	LOC100588616	ENSNLEP00000035934	ENSNLEP00000031531	E1A binding protein p300.	Runt domain-containing protein.	0.928
EP300	RUNX3	ENSNLEP00000035934	ENSNLEP00000046876	E1A binding protein p300.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.833
EP300	SMAD1	ENSNLEP00000035934	ENSNLEP00000006702	E1A binding protein p300.	Mothers against decapentaplegic homolog.	0.852
EP300	SMAD3	ENSNLEP00000035934	ENSNLEP00000041430	E1A binding protein p300.	Mothers against decapentaplegic homolog.	0.957
EP300	SOX9	ENSNLEP00000035934	ENSNLEP00000027248	E1A binding protein p300.	SRY-box transcription factor 9.	0.839
EP300	YAP1	ENSNLEP00000035934	ENSNLEP00000031727	E1A binding protein p300.	Uncharacterized protein.	0.562
HDAC4	CBFB	ENSNLEP00000016326	ENSNLEP00000005199	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Core-binding factor subunit beta.	0.455

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