Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)    
Predicted Functional Partners:
MAP2K2
Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.
  
0.998
MAPK1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.998
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
   
0.996
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
0.996
MAP3K8
Mitogen-activated protein kinase kinase kinase 8.
  
0.988
MAPK3
Mitogen-activated protein kinase.
   
 0.987
KRAS
KRAS proto-oncogene, GTPase.
   
 0.987
LAMTOR3
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.
   
 0.981
ENSNLEP00000042936
Protein kinase domain-containing protein.
   
 0.981
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
    
0.980
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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