| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CREBBP | EP300 | ENSNLEP00000011912 | ENSNLEP00000035934 | CREB binding protein. | E1A binding protein p300. | 0.999 |
| CREBBP | MED1 | ENSNLEP00000011912 | ENSNLEP00000000991 | CREB binding protein. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.771 |
| CREBBP | NCOR1 | ENSNLEP00000011912 | ENSNLEP00000017988 | CREB binding protein. | Nuclear receptor corepressor 1. | 0.811 |
| CREBBP | NCOR2 | ENSNLEP00000011912 | ENSNLEP00000002872 | CREB binding protein. | Nuclear receptor corepressor 2. | 0.761 |
| CREBBP | PPARG | ENSNLEP00000011912 | ENSNLEP00000037002 | CREB binding protein. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.966 |
| CREBBP | PPARGC1A | ENSNLEP00000011912 | ENSNLEP00000041737 | CREB binding protein. | PPARG coactivator 1 alpha. | 0.775 |
| CREBBP | RXRA | ENSNLEP00000011912 | ENSNLEP00000036994 | CREB binding protein. | Uncharacterized protein. | 0.901 |
| CREBBP | RXRB | ENSNLEP00000011912 | ENSNLEP00000008288 | CREB binding protein. | Retinoid X receptor beta. | 0.844 |
| CREBBP | RXRG | ENSNLEP00000011912 | ENSNLEP00000017861 | CREB binding protein. | Retinoid X receptor gamma. | 0.867 |
| CREBBP | SIRT1 | ENSNLEP00000011912 | ENSNLEP00000014593 | CREB binding protein. | Sirtuin 1. | 0.769 |
| EP300 | CREBBP | ENSNLEP00000035934 | ENSNLEP00000011912 | E1A binding protein p300. | CREB binding protein. | 0.999 |
| EP300 | MED1 | ENSNLEP00000035934 | ENSNLEP00000000991 | E1A binding protein p300. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.916 |
| EP300 | NCOR1 | ENSNLEP00000035934 | ENSNLEP00000017988 | E1A binding protein p300. | Nuclear receptor corepressor 1. | 0.858 |
| EP300 | NCOR2 | ENSNLEP00000035934 | ENSNLEP00000002872 | E1A binding protein p300. | Nuclear receptor corepressor 2. | 0.678 |
| EP300 | PPARG | ENSNLEP00000035934 | ENSNLEP00000037002 | E1A binding protein p300. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.968 |
| EP300 | PPARGC1A | ENSNLEP00000035934 | ENSNLEP00000041737 | E1A binding protein p300. | PPARG coactivator 1 alpha. | 0.812 |
| EP300 | RXRA | ENSNLEP00000035934 | ENSNLEP00000036994 | E1A binding protein p300. | Uncharacterized protein. | 0.854 |
| EP300 | RXRB | ENSNLEP00000035934 | ENSNLEP00000008288 | E1A binding protein p300. | Retinoid X receptor beta. | 0.828 |
| EP300 | RXRG | ENSNLEP00000035934 | ENSNLEP00000017861 | E1A binding protein p300. | Retinoid X receptor gamma. | 0.828 |
| EP300 | SIRT1 | ENSNLEP00000035934 | ENSNLEP00000014593 | E1A binding protein p300. | Sirtuin 1. | 0.900 |
