STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK3P21 (RAC1) activated kinase 3. (580 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
   
 0.985
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.937
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.930
ITSN2
Intersectin 2.
    
 0.888
GIT2
GIT ArfGAP 2.
    
 0.834
GIT1
GIT ArfGAP 1.
    
 0.783
NCK1
Cytoplasmic protein.
    
 0.716
PAK2
Non-specific serine/threonine protein kinase.
  
 
0.706
FEM1C
Fem-1 homolog C.
    
 0.703
NCK2
Cytoplasmic protein.
    
 0.690
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.