Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A2MAlpha-2-macroglobulin. (1474 aa)    
Predicted Functional Partners:
PZP
PZP alpha-2-macroglobulin like.
   
 
 0.964
PLAU
Plasminogen activator, urokinase.
    
 0.923
ALB
Albumin.
   
 0.804
MMP2
Matrix metallopeptidase 2.
    
 0.788
ITIH2
Inter-alpha-trypsin inhibitor heavy chain 2.
   
 0.787
CBX8
Chromobox 8.
    
 0.772
CBX2
Chromobox 2.
    
 0.751
KLK3
Kallikrein related peptidase 3; Belongs to the peptidase S1 family.
    
 0.737
SERPINA1
Serpin family A member 1; Belongs to the serpin family.
   
 0.734
PHC3
Polyhomeotic homolog 3.
    
 0.709
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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