| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSNLEP00000036022 | NADSYN1 | ENSNLEP00000036022 | ENSNLEP00000013084 | CTP_transf_like domain-containing protein. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.783 |
| ENSNLEP00000036022 | NAMPT | ENSNLEP00000036022 | ENSNLEP00000010796 | CTP_transf_like domain-containing protein. | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. | 0.600 |
| ENSNLEP00000036022 | NAPRT | ENSNLEP00000036022 | ENSNLEP00000038640 | CTP_transf_like domain-containing protein. | Nicotinate phosphoribosyltransferase. | 0.741 |
| ENSNLEP00000036022 | NMNAT2 | ENSNLEP00000036022 | ENSNLEP00000021889 | CTP_transf_like domain-containing protein. | Nicotinamide nucleotide adenylyltransferase 2. | 0.579 |
| ENSNLEP00000036022 | QPRT | ENSNLEP00000036022 | ENSNLEP00000019103 | CTP_transf_like domain-containing protein. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.677 |
| HAAO | KYNU | ENSNLEP00000020275 | ENSNLEP00000010945 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. | 0.993 |
| HAAO | NADSYN1 | ENSNLEP00000020275 | ENSNLEP00000013084 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.546 |
| HAAO | NAPRT | ENSNLEP00000020275 | ENSNLEP00000038640 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | Nicotinate phosphoribosyltransferase. | 0.765 |
| HAAO | QPRT | ENSNLEP00000020275 | ENSNLEP00000019103 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.737 |
| KYNU | HAAO | ENSNLEP00000010945 | ENSNLEP00000020275 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.993 |
| KYNU | NADSYN1 | ENSNLEP00000010945 | ENSNLEP00000013084 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.429 |
| KYNU | NAPRT | ENSNLEP00000010945 | ENSNLEP00000038640 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. | Nicotinate phosphoribosyltransferase. | 0.721 |
| KYNU | QPRT | ENSNLEP00000010945 | ENSNLEP00000019103 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.700 |
| NADSYN1 | ENSNLEP00000036022 | ENSNLEP00000013084 | ENSNLEP00000036022 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | CTP_transf_like domain-containing protein. | 0.783 |
| NADSYN1 | HAAO | ENSNLEP00000013084 | ENSNLEP00000020275 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. | 0.546 |
| NADSYN1 | KYNU | ENSNLEP00000013084 | ENSNLEP00000010945 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. | 0.429 |
| NADSYN1 | NAMPT | ENSNLEP00000013084 | ENSNLEP00000010796 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. | 0.424 |
| NADSYN1 | NAPRT | ENSNLEP00000013084 | ENSNLEP00000038640 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | Nicotinate phosphoribosyltransferase. | 0.774 |
| NADSYN1 | NMNAT1 | ENSNLEP00000013084 | ENSNLEP00000011413 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | Nicotinamide-nucleotide adenylyltransferase. | 0.977 |
| NADSYN1 | NMNAT2 | ENSNLEP00000013084 | ENSNLEP00000021889 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | Nicotinamide nucleotide adenylyltransferase 2. | 0.977 |
