Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NF1Neurofibromin 1. (2839 aa)    
Predicted Functional Partners:
HRAS
HRas proto-oncogene, GTPase.
   
 0.992
KRAS
KRAS proto-oncogene, GTPase.
   
 0.990
NRAS
NRAS proto-oncogene, GTPase.
   
 0.985
SPRED1
Sprouty related EVH1 domain containing 1.
    
 0.959
RRAS
RAS related.
   
 0.948
MRAS
Muscle RAS oncogene homolog.
   
 0.947
RRAS2
RAS related 2.
   
 0.947
SPRED2
Sprouty related EVH1 domain containing 2.
    
 0.844
SLC6A18
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
   
 
 0.806
ERAS
ES cell expressed Ras.
   
 0.794
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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